1. What is Total Concentration of Solute in Organic Phase?

Definition: This calculator determines the concentration of a solute in the organic phase based on its distribution ratio and aqueous phase concentration.

Purpose: It's essential for chemical engineering, pharmaceutical extraction processes, and environmental chemistry studies.

2. How Does the Calculator Work?

The calculator uses the formula:

Where:

• \( C_{org} \) — Concentration in organic phase (mol/m³)
• \( D \) — Distribution ratio (dimensionless)
• \( C_{aq} \) — Concentration in aqueous phase (mol/m³)

Explanation: The distribution ratio describes how a solute partitions between two immiscible phases, with higher values indicating greater affinity for the organic phase.

3. Importance of This Calculation

Details: Accurate calculation helps in designing extraction processes, predicting drug bioavailability, and analyzing environmental pollutant distribution.

4. Using the Calculator

Tips: Enter the distribution ratio (typically determined experimentally) and the aqueous phase concentration. Both values must be > 0.

5. Frequently Asked Questions (FAQ)

Q1: What is a typical distribution ratio value?
A: Values range from near 0 (prefers aqueous phase) to >100 (strongly prefers organic phase), depending on solute and solvent system.

Q2: How is distribution ratio different from partition coefficient?
A: Partition coefficient refers to specific molecular forms, while distribution ratio considers all forms of the solute.

Q3: What factors affect the distribution ratio?
A: Temperature, pH, solvent composition, and solute chemical properties all influence D values.

Q4: Can this calculator be used for liquid-liquid extraction?
A: Yes, it's fundamental for designing and analyzing liquid-liquid extraction processes.

Q5: What units should I use for concentration?
A: The calculator uses mol/m³, but any consistent units can be used as long as both concentrations are in the same units.