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Definition: This calculator determines the concentration of a solute in the organic phase based on its distribution ratio and aqueous phase concentration.
Purpose: It's essential for chemical engineering, pharmaceutical extraction processes, and environmental chemistry studies.
The calculator uses the formula:
Where:
Explanation: The distribution ratio describes how a solute partitions between two immiscible phases, with higher values indicating greater affinity for the organic phase.
Details: Accurate calculation helps in designing extraction processes, predicting drug bioavailability, and analyzing environmental pollutant distribution.
Tips: Enter the distribution ratio (typically determined experimentally) and the aqueous phase concentration. Both values must be > 0.
Q1: What is a typical distribution ratio value?
A: Values range from near 0 (prefers aqueous phase) to >100 (strongly prefers organic phase), depending on solute and solvent system.
Q2: How is distribution ratio different from partition coefficient?
A: Partition coefficient refers to specific molecular forms, while distribution ratio considers all forms of the solute.
Q3: What factors affect the distribution ratio?
A: Temperature, pH, solvent composition, and solute chemical properties all influence D values.
Q4: Can this calculator be used for liquid-liquid extraction?
A: Yes, it's fundamental for designing and analyzing liquid-liquid extraction processes.
Q5: What units should I use for concentration?
A: The calculator uses mol/m³, but any consistent units can be used as long as both concentrations are in the same units.