1. What is Drug Purity?

Drug Purity is the measurement of the quantity of a prevalent component of a drug substance when only that component is present. It indicates the proportion of the active pharmaceutical ingredient in a drug formulation.

2. How Does the Calculator Work?

The calculator uses the formula:

Where:

• \( Q \) — Drug Purity
• \( De \) — Effective Dose (kg)
• \( Da \) — Administered Dose (kg)
• \( B \) — Bioavailability

Explanation: The formula calculates drug purity by dividing the effective dose by the product of administered dose and bioavailability.

3. Importance of Drug Purity Calculation

Details: Accurate drug purity calculation is crucial for pharmaceutical quality control, ensuring proper dosing, and maintaining drug efficacy and safety standards.

4. Using the Calculator

Tips: Enter effective dose and administered dose in kilograms, and bioavailability as a decimal value. All values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: What is bioavailability?
A: Bioavailability is the systemically available fraction of a drug that reaches the systemic circulation unchanged.

Q2: Why is drug purity important?
A: Drug purity ensures that patients receive the correct amount of active ingredient, affecting both efficacy and safety of the medication.

Q3: What units should be used for dose measurements?
A: Both effective dose and administered dose should be measured in the same units (typically kilograms or milligrams).

Q4: How does bioavailability affect drug purity calculation?
A: Bioavailability accounts for the fraction of the administered dose that actually reaches systemic circulation, providing a more accurate purity measurement.

Q5: What is considered a good drug purity value?
A: Pharmaceutical standards typically require drug purity of 95% or higher, though specific requirements vary by medication and regulatory guidelines.